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GMP and FDA requirements must be met by pharma centrifuge during the manufacture of active drug substances. The shadow of centrifuge can be seen in every stage of API production, such as horizontal centrifuge, vertical centrifuge, ordinary centrifuge, explosion-proof centrifuge, etc. Horizontal centrifuges with wall penetration installation can be widely used in the production of API with high cleanliness requirements.
GKC Horizontal automatic scraper centrifuges with wall penetration installation is very widely used in pharmaceutical area for active drug substances production. As power and production areas of this pharma centrifuge machine can be separated totally, no cross contamination will happen. And housing of this centrifuge application can be open to show the whole drum, all residual filter cake can be removed.
A centrifuge in pharma is a specialized equipment used in the pharmaceutical industry for separating and purifying different components of a mixture based on their density, size, and shape using centrifugal force.
A centrifuge works by spinning the mixture at high speeds, causing the components to separate based on their relative densities. The heavier components are forced to the bottom of the tube or container, while the lighter components remain at the top. The separated components can then be collected and further processed or analyzed.
In the pharmaceutical industry, centrifuges are used in various applications of centrifugation in pharmaceutical industry such as cell separation, protein purification, vaccine production, drug formulation, and quality control. For example, centrifugation is used in vaccine production to separate the virus or bacteria from the growth medium, and in drug formulation to remove impurities and other unwanted particles from the final product.
The selection of the appropriate centrifuge depends on the specific application of centrifugation in pharmaceutical industry, the size and characteristics of the particles being separated, and the required throughput. There are different types of centrifuge in pharma available, including sedimentation centrifuges, ultracentrifuges, decanter centrifuges, and basket centrifuges, each with their specific applications and capabilities.
1. Separation and purification of components: Centrifuge used in pharmaceutical industry to separate and purify various components of a mixture based on their density, size, and shape. This is important in the production of drugs, vaccines, and other pharmaceutical products, where impurities and unwanted particles must be removed from the final product.
2. Improving product quality and safety: Centrifuges help to ensure that pharmaceutical products meet the required specifications and are safe for use. They help to remove impurities and other unwanted particles that can affect the quality and safety of the final product.
3. Increasing efficiency and productivity: Centrifuges can handle large volumes of samples and can separate components quickly and efficiently. This helps to increase productivity and reduce processing time, thereby improving the efficiency of pharmaceutical production.
4. Standardization and reproducibility: Centrifuge used in pharmaceutical industry. This helps to ensure reproducibility and consistency in the production of pharmaceutical products, making it easier to meet regulatory requirements and ensure product quality.
5. Research and development: Centrifuges are also used in research and development in the pharmaceutical industry to isolate and study various components of biological samples. This helps researchers to understand the characteristics and behavior of these components and develop new drugs and therapies.
Overall, Centrifuge used in pharmaceutical industry helps to ensure the quality, safety, and efficiency of pharmaceutical production.